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ZEWDIS

1.5-year-old FS Domestic Rabbit

October 26, 2022
Dr. Nicholas Jew, DVM, MedVet Hilliard
Dr. Eric Hostnik, DVM, MS, DAVCR-DI, DACVR-EDI, The Ohio State University College of Veterinary Medicine
Dr. Kayla Sands, DVM, Norton Road Veterinary Hospital

A 1 year, 8 month old female spayed domestic rabbit (Oryctolagus cuniculus domesticus) presented for exophthalmos of the right eye and persistent elevation of the nictatans.

Transverse, soft tissue of skullcaption

Transverse, standard algorithm of Rabbit in VetMouseTrap.

Transverse, bone algorithm of Rabbit in VetMouseTrap.

Dorsal, standard algorithm of Rabbit in VetMouseTrap.

  • There is a 1.43 x 2.08 x 2.04 cm hypoattenuating (HU approximately 2) mass in the region of the medial canthus; the mass causes dorsolateral displacement of the ocular globe. The margins of the hypoattenuating mass are smooth with distinct borders. There is mild expansile remodeling of the ventral osseous orbit. The mass is dorsal to the right zygomatic arch.
  • The maxillary incisors and mandibular incisors are unremarkable. All tooth roots are within normal limits. There are mild lingual points on the mandibular cheek teeth and mild labial points on the maxillary cheek teeth.
  • The nasal turbinates are symmetric with gas that abuts the mucosa overlying the osseous scrolls. The pattern of nasal turbinates is normal. The ethmoid turbinates are unremarkable. The choana is unremarkable with a gas-filled nasopharynx. The soft palate is unremarkable. The cribriform plate is unremarkable. The intracalvarial structures are unremarkable. The temporomandibular joints are congruent. The tympanic bullae are gas-filled with smooth osseous margins. The external ear canals are gas filled. The mandibular lymph nodes are symmetric and within normal limits for size and shape. The medial retropharyngeal lymph nodes are symmetric and normal for size and shape.
  • The cardiac silhouette is normal for size, shape, and margination. The pulmonary vasculature is unremarkable; the pulmonary arteries and veins are symmetric with appropriate tapering into the peripheral lungs. The pulmonary parenchyma is unremarkable. The pleural structures are
  • The trachea has a normal luminal diameter. The esophagus is soft tissue attenuating. The cranial mediastinal lymph nodes are unremarkable. The sternal lymph nodes are unremarkable. The cervical vertebrae are appropriately aligned with normal intervertebral disc spaces. The thoracic vertebrae are appropriately aligned.
  • The abdominal serosal detail is normal. The liver is normal for size with sharp margination. The hepatic parenchyma is homogeneous; the hypoattenuating branching structures within the liver represent the hepatic veins and the portal vasculature. The gallbladder is hypoattenuating to the liver with homogeneous attenuation. The spleen is smoothly marginated. The stomach contains heterogeneous soft tissue; the stomach is normal for size. The pyloroduodenal junction is normal. The small intestine is normal for size containing gas bubbles and mixed heterogeneous/homogeneous soft tissue opacity. The cecum is normal for size containing heterogeneous soft tissue. There are formed cecotropes in the colon. The kidneys are symmetric and normal for size and shape. The adrenal glands are symmetric and normal for shape. There is dependent granular mineral materials in the urinary bladder. The lymph nodes of the abdomen are within normal limits. The lumbar spine is unremarkable. The sacroiliac articulations are unremarkable. The coxofemoral joints are congruent with appropriate coverage of the femoral heads by the acetabular margins. The thigh musculature is symmetric and normal for size.
  • The ribs are symmetric and smoothly marginated. The scapular blades are normal. The scapulohumeral joints are congruent. The humeral diaphyses are normal. The elbow joints are congruent with smooth periarticular margins. The radial and ulnar diaphyses are normal. The antebrachiocarpal joint, middle carpal joint, and carpometacarpal joints are unremarkable. The carpal bones are unremarkable. The metacarpal bones are unremarkable. The forelimb interphalangeal joints are normal. The femoral diaphyses are normal. The stifle joints are normal. The tibial and fibular diaphyses are normal. The talocrural joints are congruent. The proximal intertarsal joints, distal intertarsal joints, and tarsometatarsal joints are unremarkable. The tarsal bones, metatarsal bones, and the phalanges are unremarkable.
  1. Right lacrimal cystic mass; consider dacryops or lacrimal gland cyst. A zygomatic gland mucocele/sialocele is possible. A neoplasia like a myxosarcoma or lymphoma is unlikely. The mass causes exophthalmos of the right ocular globe. There is regional, focal remodeling of the osseous orbit due to the size of the right lacrimal mass.
  2. Unremarkable left lacrimal gland.
  3. The thorax is unremarkable. There are no pulmonary nodules or intrathoracic lymphadenopathy.
  4. Sandlike urinary cystic calculi; likely dietary, calcium carbonate.
  5. Remainder of the abdomen is unremarkable.
  6. Unremarkable spine and and appendicular skeleton.
  • The rabbit underwent enucleation OD to provide access to the cystic mass. The mass was surgically excised and submitted for histopathologic evaluation.
  • Based on histopathology, the rabbit was diagnosed with focally marked chronic neutrophilic, histiocytic, lymphoplasmacytic periorbital cellulitis and adenitis accompanied by cavitary necrosis and partially encapsulating fibroplasia-fibrosis.
  • Culture and sensitivity of the cystic mass failed to grow any organisms.
  • Two weeks after surgery, the incision had healed well, and no local swelling or drainage was noted. The rabbit was noted to be doing well at home.
  • No physical examination changes indicative of recurrence developed 3 months after surgery.