4-year-old spayed female Labrador Retriever

Intermittent vomiting and diarrhea 1 month duration

  • Spleen abnormal contour, two hypoechoic ill defined areas
  • Small amount free abdominal fluid
  • Lymph nodes- abnormal size and echogenicity-hypoechoic
  • Small intestines- two areas loss of normal layers, thickened
  • Reactive omentum
  • Differential Diagnosis: 1. LSA 2. mast cell tumor 3. pythiosis 4. adenocarcinoma 5. Leiomyosarcoma. LSA- final diagnosis large cell lymphoma
  • FNA lymph node and intestinal mass, spleen